Antihistamines for Morning Sickness
Certain antihistamines such as dimenhydrinate or doxylamine, taken as your doctor advises, may relieve morning sickness.1 Doxylamine (Unisom SleepTabs) is available over-the-counter. If one of these antihistamines alone does not relieve your morning sickness, you can try taking it with vitamin B6.2 Talk to your doctor about the right dose.
Note: Do not confuse Unisom SleepTabs with Unisom SleepGels, which contain a different medicine.
A prescription medicine that combines doxylamine and vitamin B6 in one medicine (called Diclegis) is also available to treat morning sickness.
Common side effects of these medicines may include:
- Dry mouth, nose, or throat.
- Stomach upset.
- Festin M (2009). Nausea and vomiting in early pregnancy, search date May 2008. BMJ Clinical Evidence. Available online: http://www.clinicalevidence.com.
- Kelly TF, Savides TJ. (2009). Gastrointestinal disease in pregnancy. In RK Creasy et al., eds., Creasy and Resnik's Maternal-Fetal Medicine: Principles and Practice, 6th ed., pp. 1041–1057. Philadelphia: Saunders Elsevier.
|Primary Medical Reviewer||Sarah Marshall, MD - Family Medicine|
|Specialist Medical Reviewer||Kirtly Jones, MD - Obstetrics and Gynecology|
|Last Revised||August 15, 2013|
Last Revised: August 15, 2013
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