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Neuropathy, Peripheral

National Organization for Rare Disorders, Inc.

Important

It is possible that the main title of the report Neuropathy, Peripheral is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.

Synonyms

  • Mononeuritis, Peripheral
  • Mononeuritis Multiplex
  • Mononeuropathym Peripheral
  • Multiple Peripheral Neuritis
  • Peripheral Neuritis
  • Polyneuritis, Peripheral
  • Polyneuropathy, Peripheral

Disorder Subdivisions

  • Ulnar Nerve Palsy
  • Tardy Ulnar Palsy
  • Peroneal Nerve Palsy
  • Radial Nerve Palsy
  • Saturday Night Palsy

General Discussion

Peripheral neuropathy is an umbrella term that denotes a disorder of, or damage to, the peripheral nervous system. The peripheral nervous system consists of all the motor and sensory nerves that connect the brain and spinal cord to the rest of the body (i.e., the nerves outside the central nervous system). The symptoms and physical findings associated with peripheral neuropathies vary greatly from case to case and may be extremely complex.



More than 100 different peripheral neuropathies are recognized, each with a distinguishing set of symptoms, development path, and prognosis. Disorders affecting only one nerve are described as a mononeuropathies while disorders affecting more than one nerve are called polyneuropathies. If two nerves affecting different parts of the body are involved, the disorder is described as a mononeuritis multiplex.



In some cases, symptoms emerge abruptly, progress rapidly, and are slow to subside. Some chronic forms emerge only gradually and progress slowly. Some chronic forms appear to be resolved but are subject to relapses. Most often, symptoms such as pain, tingling, and/or muscle weakness start in both of the feet (bilateral) and progress up the legs. This is usually followed by symptoms in the hands that progress up the arms.

Resources

NIH/National Institute of Neurological Disorders and Stroke

P.O. Box 5801

Bethesda, MD 20824

Tel: (301)496-5751

Fax: (301)402-2186

Tel: (800)352-9424

TDD: (301)468-5981

Internet: http://www.ninds.nih.gov/



Neuropathy Association

60 East 42nd Street

Suite 942

New York, NY 10165

USA

Tel: (212)692-0662

Fax: (212)692-0668

Email: info@neuropathy.org

Internet: http://www.neuropathy.org



Genetic and Rare Diseases (GARD) Information Center

PO Box 8126

Gaithersburg, MD 20898-8126

Tel: (301)251-4925

Fax: (301)251-4911

Tel: (888)205-2311

TDD: (888)205-3223

Internet: http://rarediseases.info.nih.gov/GARD/



Center for Peripheral Neuropathy

University of Chicago

5841 South Maryland Ave, MC 2030

Chicago, IL 60637

Tel: (773)702-5659

Fax: (773)702-5577

Internet: http://peripheralneuropathycenter.uchicago.edu/



Foundation for Peripheral Neuropathy

485 Half Day Road

Suite 200

Buffalo Grove, IL 60089

Tel: (847)883-9942

Fax: (847)883-9960

Tel: (877)833-9942

Email: info@tffpn.org

Internet: http://www.foundationforpn.org



For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to MyD-H, the Dartmouth-Hitchcock patient portal. You must be a registered MyD-H user for the Lebanon, Manchester, or Nashua locations to access this site.

The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.

It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report

This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email orphan@rarediseases.org

Last Updated:  4/25/2008

Copyright  1987, 1989, 1991, 1994, 1995, 1996, 1998, 2005 National Organization for Rare Disorders, Inc.

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