Bronchopulmonary Dysplasia (BPD)
National Organization for Rare Disorders, Inc.
It is possible that the main title of the report Bronchopulmonary Dysplasia (BPD) is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.
Bronchopulmonary dysplasia (BPD) is a chronic respiratory disease that most often occurs in low-weight or premature infants who have received supplemental oxygen or have spent long periods of time on a breathing machine (mechanical ventilation), such as infants who have acute respiratory distress syndrome. BPD can also occur in older infants who experience abnormal lung development or some infants that have had an infection before birth (antenatal infection) or placental abnormalities (such as preeclampsia). Antenatal steroid treatment prior to preterm birth and early treatment with surfactant have reduced the need for high levels of respiratory support after birth.
Affected infants may have rapid, labored breathing and bluish discoloration of the skin due to low levels of oxygen in the blood (cyanosis). Infants are not born with BPD, the condition results from damage to the lungs. Although most infants fully recover from BPD, some subjects have sustained abnormalities of lung function and structure throughout adolescence and into adulthood. However, the condition can cause serious complications during infancy and often requires hospitalization and intensive medical care, especially during the first 2 years after birth.
The survival of low birth weight infants has improved steadily over the past few decades. Many infants diagnosed with BPD today are born at far earlier gestational ages than in the past. Researchers believe that these cases of BPD are less associated with injury and repair to the lungs and more likely represent an underlying disruption or abnormality affecting the development of the lungs. These infants may require chronic oxygen supplementation even without developing acute respiratory distress syndrome. These cases are sometimes referred to as "new" BPD.
American Lung Association
- 1301 Pennsylvania Ave NW
- Suite 800
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- Website: http://www.lungusa.org
British Lung Foundation
- 73-75 Goswell Road
- London, EC1V 7ER
- United Kingdom
- Tel: 2076885555
- Tel: 3000030555
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- Website: http://www.lunguk.org
Genetic and Rare Diseases (GARD) Information Center
- PO Box 8126
- Gaithersburg, MD 20898-8126
- Tel: (301)251-4925
- Fax: (301)251-4911
- Tel: (888)205-2311
- Website: http://rarediseases.info.nih.gov/GARD/
March of Dimes Birth Defects Foundation
- 1275 Mamaroneck Avenue
- White Plains, NY 10605
- Tel: (914)997-4488
- Fax: (914)997-4763
- Website: http://www.marchofdimes.com
NIH/National Heart, Lung and Blood Institute
- P.O. Box 30105
- Bethesda, MD 20892-0105
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- Website: http://www.nhlbi.nih.gov/
NIH/National Institute of Child Health and Human Development
- 31 Center Dr
- Building 31, Room 2A32
- Bethesda, MD 20892
- Fax: (866)760-5947
- Tel: (800)370-2943
- Email: NICHDInformationResourceCenter@mail.nih.gov
- Website: http://www.nichd.nih.gov/
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This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".
The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.
It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report
This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.
For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email firstname.lastname@example.org
Last Updated: 12/29/1969
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