Idiopathic Subglottic Stenosis

National Organization for Rare Disorders, Inc.

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It is possible that the main title of the report Idiopathic Subglottic Stenosis is not the name you expected.

Disorder Subdivisions

  • None

General Discussion

Idiopathic subglottic stenosis (iSGS) is a narrowing (stenosis) of a specific portion of the windpipe (trachea) known as the subglottis (just below the vocal cords). Idiopathic means that the underlying cause of this narrowing is unknown. Most cases are associated with the formation of scar tissue (fibrosis) and inflammation in the affected area. Symptoms may include shortness of breath upon exertion (dyspnea), hoarseness, and a high-pitched wheezing sound when breathing in or out (stridor). The disorder occurs almost exclusively in women. The condition often recurs despite treatment.

Supporting Organizations

Genetic and Rare Diseases (GARD) Information Center

PO Box 8126
Gaithersburg, MD 20898-8126
Tel: (301)251-4925
Fax: (301)251-4911
Tel: (888)205-2311

For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders (NORD). For a full-text version of this report, go to and click on Rare Disease Database under "Rare Disease Information".

The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only.

It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report.

This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

Last Updated:  9/10/2015
Copyright  2015 National Organization for Rare Disorders, Inc.