Health Information



Mesenchymal Chondrosarcoma

National Organization for Rare Disorders, Inc.


It is possible that the main title of the report Mesenchymal Chondrosarcoma is not the name you expected.

Disorder Subdivisions

  • Extraskeletal Mesenchymal Chondrosarcoma

General Discussion

Mesenchymal chondrosarcoma is an extremely rare, often aggressive form of cancer. It is a variant type of conventional chondrosarcoma. Conventional chondrosarcoma is a form of bone cancer that arises from cartilage cells. Cartilage is the specialized tissue that serves as a buffer or cushion at joints. Most of the skeleton of an embryo consists of cartilage, which is slowly converted into bone. Approximately two-thirds of cases of mesenchymal chondrosarcoma affect the bones, especially the spine, ribs or jaws. The remaining cases occur in areas of the body other than bone (extraskeletal, that is, occurring in soft tissues like muscle and fat). Unlike conventional chondrosarcomas, mesenchymal chondrosarcomas occur with greater frequency in young adults. This form of cancer often spreads (metastasizes) to other areas of the body and can cause life-threatening complications.


American Cancer Society, Inc.

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National Cancer Institute

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Tel: (301)435-3848

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National Coalition for Cancer Survivorship

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Sarcoma Foundation of America

9899 Main Street Ste 204

Damascus, MD 20872


Tel: (301)253-8687

Fax: (301)253-8690



Sarcoma Alliance

775 E. Blithedale #334

Mill Valley, CA 94941


Tel: (415)381-7236

Fax: (415)381-7235



Rare Cancer Alliance

1649 North Pacana Way

Green Valley, AZ 85614



Genetic and Rare Diseases (GARD) Information Center

PO Box 8126

Gaithersburg, MD 20898-8126

Tel: (301)251-4925

Fax: (301)251-4911

Tel: (888)205-2311

TDD: (888)205-3223



76 Ellsworth Street

San Francisco, CA 94110

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Northwest Sarcoma Foundation

P.O. Box 91460

Portland, OR 97291

Tel: (503)954-5740



For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to and click on Rare Disease Database under "Rare Disease Information".

The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.

It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report

This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site or email

Last Updated:  1/3/2012

Copyright  2008, 2012 National Organization for Rare Disorders, Inc.

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