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aflibercept ophthalmic

Pronunciation: a FLIB er sept off THAL mik

Brand: Eylea

What is the most important information I should know about aflibercept ophthalmic?

Multum donot

You should not receive aflibercept if you are allergic to it, or if you have cataracts or glaucoma, or any type of bacterial, fungal, or viral infection in or around your eyes.

Multum emt

Call your doctor at once if you have eye pain or redness, swelling or puffiness around your eyes, or sudden vision problems at any time during treatment.

What is aflibercept ophthalmic?

Aflibercept is made from a human antibody fragment. It works by keeping new blood vessels from forming under the retina (a sensory membrane that lines the inside of the eye). In people with a certain type of eye disease, new blood vessels grow under the retina where they leak blood and fluid. This is known as the "wet form" of macular degeneration.

Aflibercept ophthalmic (for the eyes) is used to treat wet age-related macular degeneration. Aflibercept is also used to treat swelling in the retina caused by a blockage in the blood vessels.

Aflibercept ophthalmic may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before using aflibercept ophthalmic?

Multum donot

You should not receive aflibercept if you are allergic to it, or if you have:

  • eye conditions such as cataracts or glaucoma; or
  • any type of bacterial, fungal, or viral infection in or around your eyes.
Multum nopreg

FDA pregnancy category C. It is not known whether aflibercept will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

Multum nobrfeed

It is not known whether aflibercept passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using aflibercept.

How is aflibercept ophthalmic given?

Aflibercept ophthalmic is given as an injection into your eye. Your doctor will use a medicine to numb your eye before giving you the injection. You will receive this injection in your doctor's office or other clinic setting.

For a short time after your injection, your eyes will be checked periodically to make sure the injection has not caused any side effects.

Aflibercept is usually given once every 4 weeks for the first 3 months, and then once every 8 weeks. Follow your doctor's dosing instructions very carefully.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your aflibercept injection.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using aflibercept ophthalmic?

Multum dizzy

This medication may cause blurred vision. Be careful if you drive or do anything that requires you to be able to see clearly.

What are the possible side effects of aflibercept ophthalmic?

Multum emt

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Multum donot

Call your doctor at once if you have a serious side effect such as:

  • eye pain or redness, swelling around your eyes;
  • sudden vision problems;
  • seeing flashes of light or "floaters" in your vision;
  • eyes being more sensitive to light;
  • sudden numbness or weakness, especially on one side of the body; or
  • sudden severe headache, confusion, problems with speech or balance.

Less serious side effects may include:

  • watery eyes;
  • blurred vision;
  • swelling of the eyelids; or
  • mild eye pain or discomfort after the injection.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect aflibercept ophthalmic?

It is not likely that other drugs you take orally or inject will have an effect on aflibercept used in the eyes. But many drugs can interact with each other. Tell your doctor about all medicines you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about aflibercept ophthalmic.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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