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ropivacaine

Pronunciation: roe PIV a kane

Brand: Naropin, Naropin Polyamp, Naropin SDV

What is the most important information I should know about ropivacaine?

Multum donot

Tell your doctor if you have ever had an allergic reaction to any type of numbing medicine.

Before receiving ropivacaine, tell your doctor if you have liver disease, heart disease, kidney disease, or a heart rhythm disorder.

Multum emt

Tell your caregivers at once if you have a serious side effect such as: confusion, feeling like you might pass out, problems with speech or vision, ringing in your ears, numbness or tingling around your mouth, seizure, weak or shallow breathing, fast or slow heart rate, weak pulse, gasping, or feeling unusually hot.

This medication can cause numbness over a large portion of your body. Take care to avoid injury before the feeling has returned completely.

Multum donot

Some numbing medications can have long-lasting or delayed effects. Talk to your doctor if you have concerns about this risk. Call your doctor if you have joint pain or stiffness, or weakness in any part of your body that occurs after your surgery, even months later.

What is ropivacaine?

Ropivacaine is an anesthetic (numbing medicine) that blocks the nerve impulses that send pain signals to your brain.

Ropivacaine is used as a local (in only one area) anesthesia for a spinal block, also called an epidural. The medication is used to provide anesthesia during a surgery or C-section, or to ease labor pains.

Ropivacaine may also be used for purposes not listed in this medication guide.

What should I discuss with my health care provider before receiving ropivacaine?

Multum donot

Tell your doctor if you have ever had an allergic reaction to any type of numbing medicine.

To make sure you can safely receive ropivacaine, tell your doctor if you have any of these other conditions:

  • liver disease;
  • heart disease;
  • kidney disease; or
  • a heart rhythm disorder.

FDA pregnancy category B. Ropivacaine is not expected to harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Multum nobrfeed

It is not known whether ropivacaine can pass into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How is ropivacaine given?

Ropivacaine is given as an injection through a needle placed into an area of your middle or lower back near your spine. You will receive this injection in a hospital or surgical setting.

Multum emt

Your breathing, blood pressure, oxygen levels, and other vital signs will be watched closely while you are receiving ropivacaine.

Multum donot

Some numbing medications can have long-lasting or delayed effects. Talk to your doctor if you have concerns about this risk. Call your doctor if you have joint pain or stiffness, or weakness in any part of your body that occurs after your surgery, even months later.

What happens if I miss a dose?

Since ropivacaine is given as needed before a surgery or other medical procedure, you are not likely to be on a dosing schedule.

What happens if I overdose?

Multum emt

Tell your caregivers right away if you think you have received too much of this medicine.

Overdose symptoms may include severe forms of some of the side effects listed in this medication guide.

What should I avoid after receiving ropivacaine?

This medication can cause numbness over a large portion of your body. Take care to avoid injury before the feeling has returned completely.

What are the possible side effects of ropivacaine?

Multum emt

Get emergency medical help if you have any of these signs of an allergic reaction: hives or red skin rash; dizziness; sneezing; difficulty breathing; nausea or vomiting; sweating; swelling of your face, lips, tongue, or throat.

Multum donot

Tell your caregivers at once if you have any of these serious side effects:

  • feeling anxious, restless, confused, or like you might pass out;
  • problems with speech or vision;
  • ringing in the ears, metallic taste, numbness or tingling around your mouth, or tremors;
  • seizure (convulsions);
  • weak or shallow breathing;
  • slow heart rate, weak pulse; or
  • fast heart rate, gasping, feeling unusually hot.

Less serious side effects include:

  • nausea, vomiting;
  • headache, back pain;
  • fever;
  • itching;
  • numbness or tingly feeling; or
  • problems with urination or sexual function.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect ropivacaine?

Many drugs can interact with ropivacaine. Below is just a partial list. Tell your doctor if you are using:

  • birth control pills or other hormones;
  • cimetidine (Tagamet);
  • cyclobenzaprine (Flexeril);
  • interferon (Actimmune, Roferon, Intron, Rebetron, and others);
  • ondansetron (Zofran);
  • propranolol (Inderal);
  • theophylline (Elixophyllin, Respbid, Slo-Bid, Theobid, Theo-Dur);
  • verapamil (Calan, Covera, Isoptin, Verelan);
  • warfarin (Coumadin);
  • a heart rhythm medication such as amiodarone (Cordarone, Pacerone), bretylium (Bretylan, Tosylate), dofetilide (Tikosyn), ibutilide (Corvert), mexiletine (Mexitil), or sotalol (Betapace);
  • antidepressants such as amitriptyline (Elavil, Etrafon), clomipramine (Anafranil), fluvoxamine (Luvox), imipramine (Janimine, Tofranil); or
  • medicines to treat psychiatric disorders, such as clozapine (Clozaril, FazaClo), haloperidol (Haldol), olanzapine (Zyprexa, Zydis).

This list is not complete and other drugs may interact with ropivacaine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

Where can I get more information?

Your doctor or pharmacist can provide more information about ropivacaine.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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