Health Information

 

 

trientine

Pronunciation: TRYE en teen

Brand: Syprine

What is the most important information I should know about trientine?

Before using trientine, tell your doctor if you are allergic to any drugs, or if you have rheumatoid arthritis, a kidney or bladder condition called cystinuria, or a liver condition called biliary cirrhosis.

Multum water

Take the trientine capsule with water. Do not take trientine with milk.

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Take trientine on an empty stomach, at least 1 hour before or 2 hours after eating a meal or snack or taking any other medicines.

Multum nocrush

Do not chew or open a trientine capsule. Swallow the pill whole.

Do not use a capsule that has been accidentally broken. The medicine from a broken capsule can be dangerous if it gets on your skin. If skin contact occurs, rinse the area thoroughly with plain water. Watch for signs of skin irritation and call your doctor if you develop a rash.

You may need to take your temperature every night for at least the first month of treatment with trientine. Call your doctor if you have a fever.

What is trientine?

Trientine is a chelating (KEE-late-ing) agent. A chelating agent is capable of removing a heavy metal, such as lead, mercury, or copper, from the blood.

Trientine is used to treat Wilson's disease in people who cannot take penicillamine (Cuprimine, Depen).

Wilson's disease is a genetic metabolic defect that causes excess copper to build up in the body.

Trientine may also be used for purposes not listed in this medication guide.

What should I discuss with my health care provider before taking trientine?

Multum donot

You should not use this medication if you are allergic to trientine.

Before using trientine, tell your doctor if you are allergic to any drugs, or if you have:

  • rheumatoid arthritis;
  • a kidney or bladder condition called cystinuria; or
  • a liver condition called biliary cirrhosis.

If you have any of these conditions, you may need dose adjustments or special tests during treatment.

Multum nopreg

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Multum nobrfeed

It is not known whether trientine passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take trientine?

Take this medication exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Multum water

Take the trientine capsule with water. Do not take trientine with milk.

Multum icon26

Take trientine on an empty stomach, at least 1 hour before or 2 hours after eating a meal or snack or taking any other medicines.

Trientine is usually taken 2 to 4 times each day. Follow your doctor's instructions.

Multum nocrush

Do not chew or open a trientine capsule. Swallow the pill whole.

Do not use a capsule that has been accidentally broken. The medicine from a broken capsule can be dangerous if it gets on your skin. If skin contact occurs, rinse the area thoroughly with plain water. Watch for signs of skin irritation and call your doctor if you develop a rash.

You may need to take your temperature every night for at least the first month of treatment with trientine. Call your doctor if you have a fever.

To be sure this medication is helping your condition, your blood will need to be tested often. Your iron levels will also be checked to make sure they don't get too low. Do not miss any scheduled appointments.

Multum refig

Store this medication in the refrigerator and do not allow it to freeze.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

A trientine overdose is not expected to produce life-threatening symptoms.

What should I avoid while taking trientine?

Avoid eating, drinking milk, or taking other medications within 1 hour before or after taking trientine.

Multum donot

Do not take any vitamins or mineral supplements unless your doctor tells you to. You may occasionally need to take an iron supplement, but follow your doctor's instructions.

What are the possible side effects of trientine?

Multum emt

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Multum emt

Call your doctor at once if you have any of these serious side effects:

  • cough, trouble breathing;
  • pale skin, easy bruising or bleeding, weakness;
  • tired feeling, muscle or joint pain, swollen glands;
  • seizure (convulsions);
  • muscle weakness, dropping eyelids, double vision; or
  • problems with speech, balance, walking, lifting, chewing, or swallowing;

Less serious side effects include:

  • skin rash;
  • muscle spasm or contractions;
  • heartburn;
  • stomach pain;
  • loss of appetite; or
  • skin flaking, cracking, or thickening;

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect trientine?

There may be other drugs that can interact with trientine. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about trientine.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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