The hemoglobin E trait is the presence of an abnormal type of the
oxygen-carrying substance in red blood cells (hemoglobin) called hemoglobin E.
Because people who have hemoglobin E trait also have some normal hemoglobin
(hemoglobin A), they rarely have problems from the condition but can pass on
the trait to their children.
If a person inherits hemoglobin E from both parents, he or she has
no normal hemoglobin (hemoglobin A) and has what is called hemoglobin EE, in
which the red blood cells are smaller than normal. A person who has hemoglobin
E with little or no normal hemoglobin may have mild anemia.
E. Gregory Thompson, MD - Internal Medicine & Joseph O'Donnell, MD - Hematology, Oncology